Validation and classification of protein structures
نویسندگان
چکیده
منابع مشابه
Validation of protein crystal structures.
Since the process of building and refining a model of a biomacromolecule based on crystallographic data is subjective, quality-control techniques are required to assess the validity of such models. During the 1990s, much experience was gained; the methods used and some of the lessons learned are reviewed here. In addition, an extensive compendium of quality criteria and quality-control methods ...
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Transmembrane (TM) proteins comprise some 15% to 30% of the proteome, and the number of reported 3D structures has grown rapidly over the past decade. Nevertheless, owing to technical difficulties, the vast majority of TM protein structures are yet to be determined. Computational modeling techniques can be used to provide the essential structural data needed to shed light on structure-function ...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2005
ISSN: 0108-7673
DOI: 10.1107/s0108767305098223